Duloxetine, often known as Cymbalta, is a medicine that is primarily used to treat serious depression, generalized anxiety disorder, fibromyalgia, and neuropathic pain. It is a member of the class of drugs known as selective reuptake inhibitors of norepinephrine and serotonin. This comprehensive guide seeks to investigate the efficacy, advantages, and application of Duloxetine 60 mg in a variety of diseases.